Stalking hypertension. For example, one test-tube study found that celery seed extract fought off H. pylori bacteria, which are found in the digestive tract of certain individuals and may lead to stomach ulcers (25, 26). 2016;128(7):682-3. Strain the seeds from the water and enjoy. These benefits might reduce the frequency and severity of painful gout attacks. Tuetun, B., Choochote, W., Pongpaibul, Y., Junkum, A., Kanjanapothi, D., Chaithong, U., Jitpakdi, A., Riyong, D., and Pitasawat, B. Celery-based topical repellents as a potential natural alternative for personal protection against mosquitoes. J Ethnopharmacol 2021;264:113400. What Are the Benefits of Celery Seed Tea? 9 An infusion of celery root increased GSH and total antioxidant capacity, and celery leaf water extract increased GSH but had no effect on total antioxidant capacity. It contains allergens that may provoke severe allergic reactions, including anaphylaxis, reports the 2017 Pharmacognosy Review study. J.Emerg.Med. These extracts have been standardized to contain certain percentages of beneficial compounds, such as luteolin or 3nB. There are plenty of celery seed supplements on the market to explore. Taking celery juice with aminopyrine might increase the effects and side effects of aminopyrine. Bleeding may occur. IMPORTANT: Celery seed and celery extract should be avoided by pregnant women. For these reasons, you should take herbs under the supervision of a health care provider. Egan, C. L. and Sterling, G. Phytophotodermatitis: a visit to Margaritaville. Herbalists recommend celery for treatment of arthritis, nervousness, and hysteria. The safety of taking celery oil and seeds if you are breastfeeding is unknown, so it's best to avoid their use if that's the case. A case of Apium graveolens (Celery) induced hyperthyroidism. Celery seeds extract is generally safe to consume and may promote overall health. Influence of certain essential oils on carcinogen-metabolizing enzymes and acid-soluble sulfhydryls in mouse liver. 1990;126(10):1334-1336. Including magnesium-rich foods like celery seeds in your diet may reduce your risk of type 2 diabetes. This is only a brief summary of general information about this product. Zheng GQ, Kenney PM, Zhang J, Lam LK. Our Celery Seed Extract is concentrated and standardized to contain 85% 3-n-butylphthalide as total phthalides. Ann.Dermatol Venereol 2005;132(6-7 Pt 1):566-567. 2013;16(6):558-63. Indias University College of Sciences Department of Biochemistry studied 35 commonly used Indian spices, including celery, cumin, tamarind and garlic (x). Adv Orthop. All rights reserved. View abstract. Magnesium plays an important role in blood sugar control and helps increase your cells response to insulin, a hormone that regulates blood sugar levels (21, 22, 23). The stem is often eaten raw or as a cooked vegetable. Concerns for Pregnant Women Pregnant women should avoid large doses of celery and celery seed as it can induce bleeding and uterine contractions. Is apple cider vinegar an effective treatment for gout? Use sunscreen or sunblock lotions. Although herbal remedies are generally accepted as complementary and alternative therapies in combination with other medications, herbs can have side effects and interact with other herbs, supplements and medications. Celery seeds are full of vitamins and minerals including vitamin C, folate, vitamin B6 and vitamin K (x). Tsi D, Das NP, Tan BK. 1st ed. These compounds as well as the major component Sedanolide appear to have general antioxidative properties and have traditionally been used as a diuretic. Allergy. View abstract. Iron is a mineral essential for producing red blood cells. View abstract. So it could be celery, another food, or some combination of foods that lowered their risk of cancer. The Department of Pharmacology at the University of Singapore put mice on a high-fat diet for eight weeks. In addition, potential celery seed benefits include the treatment of ailments such as edema, gout, flatulence, chronic pneumonia and obesity. Bleeding may occur. Pregnant and nursing women should avoid eating celery seeds as they may cause uterine bleeding and premature contractions (x). Yusni Y, Zufry H, Meutia F, Sucipto KW. (2017). Im not sure what the problem is. Ground celery seed is often referred to as celery powder. Research has shown that celery seed may be dangerous in pregnant women, as it may cause miscarriage when taken in large doses. An article in the 2013 Journal of Drug Discovery and Therapeutics reports that celery and celery seed tea are often used as a diuretic, which means it helps the body eliminate water by increasing urine output. View abstract. Am J Health Syst Pharm. Celery seed has been used as medicine for thousands of years in the Eastern world. Their flavor is warm and bitter. These seeds have usually been treated with chemicals. Celery is commonly consumed as a vegetable and its components such as seeds are commonly used as a food seasoning ingredient. During ancient times, Indian Ayurvedic medicine used celery seed to treat colds, flu, water retention, poor digestion, different types of arthritis, and certain diseases of the liver and spleen. When your calcium intake is inadequate for extended periods, your body compensates by pulling calcium from your bones. Moneret-Vautrin, D. A. and Kanny, G. [Food-induced anaphylaxis. Boffa, M. J., Gilmour, E., and Ead, R. D. Celery soup causing severe phototoxicity during PUVA therapy. Celery seeds are a great source of magnesium, with one tablespoon (6.5 grams) providing 12% of the RDI. Int Arch Allergy Immunol 2005;136(3):230-238. Celery might also make the skin more sensitive to sunlight. Celery seeds contain antioxidants and anti-inflammatory compounds. Talk with your healthcare provider before using celery if you are taking lithium. Other organic components include isovalerianic aldehyde, propionic aldehyde, and acetaldehyde.Christensen 2006, Garg 1980, Khan 2009, Madjarova 1979, Marongiu 2013, Nagella 2012, In in vitro studies, luteolin extracted from celery suppressed proinflammatory cytokines and upregulated cyclooxygenase expression.Christensen 2006, Kasiri 2018, Kim 2014, Park 2013 Further studies have suggested glycosides from the ethanol whole plant extract possess anti-inflammatory effects and inhibit nitric oxide production.Zhu 2017, Antifungal, antibacterial, and antiprotozoal activity has been described for celery oil.Baananou 2013, Marongiu 2013, Nagella 2012, Nguyen 2014 Activity against uropathogenic Escherichia coli bladder and kidney infections in rodents has been demonstrated.Sarshar 2018, Antioxidant activity has been demonstrated and may account for several observed effects of celery.Kooti 2017 Fresh celery flavonoid extracts reduced oxidative stress in rats and mice, as measured in the liver, mitochondria, and spermatozoa.Cao 2012, Choi 2011, Kolarovic 2010, Kooti 2014, Li 2014, Studies have focused on the role of apigenin, extracted from celery seed, as a potential chemotherapeutic agent. Be sure to wear sunblock and protective clothing when spending time in the sun. Sarshar S, Sendker J, Qin X, et al. Antihypertensive effect of celery seed on rat blood pressure in chronic administration. Another study observed similar antibacterial benefits of celery seed extract against certain bacteria, yeast, and mold strains. Ann.Gastroenterol Hepatol (Paris) 1995;31(4):256-263. Celery is POSSIBLY SAFE for most people when taken by mouth or applied to Celery stem, oil, and seeds are commonly consumed in foods. Again, no side effects were noted other than the diuretic effect with no changes in the sodium and potassium balance. The celery seed extract appeared to be particularly helpful for sufferers of gout, as 3nB appears to lower the production of the uric acid that causes gout by inhibiting the enzyme xanthine oxidase. Am J Health Syst Pharm 2000;57:1221-7. Al-Asmari AK, et al. Biochim Biophys Acta. The celery plant is slender and stands about 2 to 3 feet tall. Celery seeds are a great source of non-heme iron. 3-31-1984;13(14):871-874. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Celery stalks and celery juice are a healthy food choice, but they dont contain as many of the beneficial compounds as the seeds and oil. However, taking high dosages of celery seed extracts and supplements may come with risks in certain people. 3 Cancer Preventive Activity Maintaining healthy blood sugar levels is important for reducing your risk of type 2 diabetes and heart disease (19, 20). Other medications: Celery seed may interact with lithium, thyroid medications, and sedatives. This article tells you all you need to know about celeriac, Acid reflux or GERD can lead to some unpleasant symptoms, like heartburn, a sour taste in the mouth, and even difficulty swallowing. Theyre sold as whole seeds, crushed, or as a ground spice. For this reason, you should consult your doctor before introducing celery seeds into your diet, especially if you are pregnant, nursing or taking any prescription medications. A new French multicenter study]. Celery has also been prescribed as an antiflatulent, antilactogen, and aphrodisiac.Al-Asmari 2017, Bisset 1994, Garfield 1985, The celery leafstalk is high in minerals, including sodium, potassium, calcium, magnesium, and iron and nitrates; however, it is a relatively poor source of vitamins except for vitamin C.Afourtit 2015, Meng-Yao 2018. Lithium: Celery seed may alter how this medication is excreted in the body. We include products we think are useful for our readers. Severe phototoxic burn following celery ingestion. Data sources include IBM Watson Micromedex (updated 1 May 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. 2000;57(13):1221-1227. In fact, each pill has a higher dosage of celery seed extract plus the addition of the tart cherry, and at a lower price. Along with a healthy diet, seeds can help reduce blood sugar, cholesterol and blood pressure. Maljaei MB, Moosavian SP, Mirmosayyeb O, Rouhani MH, Namjoo I, Bahreini A. Research suggests that certain compounds in celery seed may have benefits in treating gout. 5 Healthy Benefits of Adding Celery to Your Diet. 2003;41:235-239. Although the results demonstrated that celery could reduce the uric acid level in mice, no human studies have been conducted. The dose depends on what you are taking it for and which form you are taking, such as celery seed oil capsules or tablets, extract, or whole celery seeds. View abstract. All rights reserved. This article explores Parmesan cheese's nutritional benefits, uses, and potential. Theyre most commonly added to soups and other savory recipes, but can also be used to make tea. Without enough dietary iron, your body cannot produce enough red blood cells. Monitor therapy.Hui 2009, Nonsteroidal anti-inflammatory agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of nonsteroidal anti-inflammatory agents. (2017). If the celery plant is infected with the fungus Sclerotinia sclerotiorum, skin contact can cause dermatitis in sensitive people, according to the Journal of Drug Discovery and Therapeutics. As a member of the parsley family, it is prominent in American cooking. However, celery was just one part of their diet. 2004;98(4):407-17. Though small in size, celery seeds are of great nutritional value and provide many health benefits. Levothyroxine is used for low thyroid function. Deficiency in either of these nutrients may lead to chronic bone diseases like osteoporosis (11, 12, 13). 2004;29(2):340-6. J Midwifery Womens Health 2009;54:401-4. You can make your own by pouring boiling water over 1 tablespoon (6.5 grams) of ground seeds and steeping the mixture for roughly 10 minutes. Singh A, Handa SS. Celery seed contains compounds that may be beneficial in the treatment of gout. Through dietary interventions, you may be able to reduce the levels of uric acid in the blood and minimize painful flare-ups. View abstract. 1995;49:119-126. DOI: Vieira AT, et al. Combined with anise and saffron, celery seed extract is used to treat menstrual discomfort and reduce fluid retention(x). Celery seeds contain methanolic and hexane extracts, which help with circulation. More importantly, celery seeds may be useful in the treatment of hypertension help normalize blood pressure.(x). For example, theyre a great source of essential minerals like calcium, manganese, and iron. One tablespoon (6.5 grams) of celery seeds provides ( 2 Trusted Source ): 1 Calories: 25 calories 2 Carbs: 2 grams 3 Protein: 1 gram 4 Fat: 2 grams 5 Fiber: 1 gram 6 Calcium: 12% of the Reference Daily Intake (RDI) 7 Zinc: 6% of the RDI 8 Manganese: 27% of the RDI 9 Iron: 17% of the RDI 10 Magnesium: 9% of the RDI More items Asia Pac J Pharmacol. Banerjee S, Sharma R, Kale RK, Rao AR. Sultana S, Ahmed S, Jahangir T, Sharma S. Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development. Scientific Name(s): Apium graveolens L. var dulce (Mill.) Miller L. Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Liu CY, et al. Nahid K, Fariborz M, Ataolah G, Solokian S. The effect of an Iranian herbal drug on primary dysmenorrhea: a clinical controlled trial. However, people who take the following medicines should ask their doctors before taking celery seed. Ayurvedic medicine uses celery seed to treat water retention, colds and flu, poor digestion, different types of arthritis and certain diseases of the liver and spleen, according to Penn State Hershey Medical Center. The most notable compounds in celery seed include: These compounds have been researched for their role in inflammation and uric acid production, which is a driving force behind the severity of gout attacks. As always, its important to consult your doctor before starting a new herbal supplement. In the UK Women's Cohort Study conducted in 13,958 women (with approximately 4 years of follow-up), consumption of an additional portion of celery (among other plants) was inversely associated with sleep duration.Noorwali 2018, Limited studies in rodents suggest celery seed extract possesses hypoglycemic effects.Yusni 2018, Very limited clinical data exist regarding the effects of celery leaf or seed extract in diabetes. Cheung MC, Lin LY, Yu TH, Peng RY. Allergy 2001;56(1):82-83. Johansson, S. G., Dannaeus, A., and Lilja, G. The relevance of anti-food antibodies for the diagnosis of food allergy. Almost 70% of older adults use them. However, herbs can have side effects and interact with other herbs, supplements, or medications. 1985;3:85. Australian Prescriber 2001;24:6-7. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. In a recent study, researchers discovered that exposing certain cells to 3nB reduced both oxidative stress and pro-inflammatory pathways. Springhouse, PA: Springhouse Corp., 1999. Clinical trials guiding celery dosage are limited. Arch.Dermatol. This product may be unsafe when used before surgery or other medical procedures. The dosage 2005 - 2023 WebMD LLC, an Internet Brands company. But if youre experiencing painful symptoms of gout and are interested in exploring alternative treatment options, speak with your doctor for more information. Avoid celery seed extract if you have ever experienced an allergic reaction after consuming celery (x). Inhibition of hepatic xanthine dehydrogenase and xanthine oxidase was suggested.Dolati 2018, Clinical trials guiding celery dosage are limited. Bleeding may occur. Celery promotes weight loss, helps to detoxify the liver and boosts lipid metabolism since it is rich in electrolytes, antioxidants, and vitamins B and C (x). View abstract. Taking celery root along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Celeriac, or celery root, is a relatively unknown root vegetable packed with nutrients. In light of the fact that celery seeds may interact with some medications, including lithium, thyroid medications and blood-thinning drugs, you should consult your doctor before taking celery seed supplements (x). If you want to try the celery seed powder, I'd View abstract. Though celery seeds are most commonly used as a cooking spice, theyre also available in other supplemental forms: These forms offer a concentrated dose of celery seed. Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet. Online ahead of print. Field evaluation of G10, a celery (Apium graveolens)-based topical repellent, against mosquitoes (Diptera: Culicidae) in Chiang Mai province, northern Thailand. One tablespoon (6.5 grams) of celery seeds provides (2): Celery seeds are low in calories, with a tablespoon providing about 25 calories. Objective: To evaluate the efficacy of a standardized extract of celery seed, 150 mg/d, supplying 85% 3-n-butylphthalide (3nB) in mild to moderate hypertensive Clin Exp Allergy 1996;26:1161-70. J Allergy Clin Immunol 1983;71(4):407-411. Symptoms of celery allergy can afflict your mouth, with itching and swelling of the lips, tongue and throat, reports the University of Nebraska - Lincoln. Potential interactions between alternative therapies and warfarin. Bleeding may occur. 3-n-butylphthalide (3nB) is another compound from celery that may have benefits against gout inflammation. WebCelery stem, oil, and seeds are commonly consumed in foods. Information from this source is evidence-based and objective, and without commercial influence. You should talk with your health care provider for complete information about the risks and benefits of using this product. Celery seed extract is most often used for Cardiovascular Health and Kidney & Urinary Health. These results indicate that celery seed may help reduce gout-related inflammation. In one trial, dl-3-n-butylphthalide 400 mg orally daily (given as one 200 mg capsule twice daily) as part of a 90-day treatment regimen was used to improve outcomes in patients with acute ischemic stroke. Therefore, researchers suggest that extract from the seeds may have potential as a natural food preservative (27). For this reason, it is important to consult with your healthcare provider before taking supplemental celery seed. A study published in Progress in Drug Research, concluded that celery seed extract could be just as effective at reducing inflammation as aspirin and ibuprofen (x). View abstract. Effect of celery extract on thyroid function; is herbal therapy safe in obesity? Some people who are allergic to birch pollen may also be allergic to celery seed. View abstract. Further studies are needed to confirm these results so, to play it safe, monitor your blood pressure if you are taking a celery supplement. 2008;63(2):243-4. 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